In a small bowl, combine the ancho chili powder, garlic powder, paprika, smoked paprika, cayenne pepper, onion powder, dry minced onion, cumin, salt and pepper. Set aside.
Brown the ground meat in a large stock pot over medium heat. If there are any large chunks, break them up with a wooden spoon. Season to taste with salt, pepper, garlic powder and onion powder as it cooks. Stir in 1 Tbsp. of the Worcestershire sauce. Remove the meat from the pot.
Grate the onions using a box grater or food processor. Add them to the pot with the diced green bell pepper. Saute the onions and peppers until soft.
Stir in the minced garlic. Season again with salt and pepper. Stir in the small bowl of dry spices and the remaining Worcestershire sauce.
Add the browned meat back to the pot.
Pour in the tomatoes and masa flour. Stir well to combine. Simmer over low heat for 20-30 minutes and up to several hours. Serve warm.